In 2025 (I refer to the update performed on 29/10/2025), the Italian National Institute of Health (Istituto Superiore di Sanità , ISS)  released the updated version of the Guidelines for the Diagnosis and Treatment of Autism Spectrum Disorder (ASD) in Children and Adolescents . The document, developed by a multidisciplinary working group  coordinated by Maria Luisa Scattoni  and Primiano Iannone , constitutes an essential reference for clinical practice and the organization of